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Semaglutide functions as a receptor agonist for glucagon-like peptide-1 (GLP-1), replicating the effects of this hormone naturally produced in the body. GLP-1, elicited by food intake from the intestine, triggers insulin release, thereby reducing blood sugar levels. 

Tirzepatide is a novel medication classified as a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. It's developed for the treatment of type 2 diabetes and obesity. This dual action helps regulate blood sugar levels by stimulating insulin release and decreasing glucagon secretion, while also promoting weight loss